International Indian Scientist Awards

  A Study on How Metal Complexes Fight Cancer | The Science Behind Anticancer Chelators! #sciencefather #CancerResearch #MetalComplexes Metal complexes have emerged as a promising frontier in cancer treatment, offering unique mechanisms to target and destroy cancer cells while minimizing harm to healthy tissues. This study explores the fascinating world of anticancer chelators —specialized compounds that bind to metal ions, creating complexes capable of disrupting essential biological processes in cancer cells. These complexes can interfere with DNA replication, generate reactive oxygen species, and inhibit tumor growth pathways, making them valuable tools in oncology research. From platinum-based drugs like cisplatin to newly developed metal complexes involving ruthenium, gold, and copper, scientists are uncovering innovative ways to harness their chemical properties for medical breakthroughs. The selective targeting ability of anticancer chelators not only enhances therapeutic e...

Har Gobind Khorana: The Genetic Code Breaker and Nobel Laureate Har Gobind Khorana, an Indian -American biochemist, was a pivotal figure in unraveling the mysteries of the genetic code, the fundamental language of life. His groundbreaking work in the 1960s, conducted in collaboration with his team, elucidated how the sequence of nucleotides in DNA dictates the arrangement of amino acids in proteins. Key contributions and impact Decoding the Genetic Code:  Khorana's meticulous experiments helped establish the codon sequences of RNA that correspond to each amino acid, providing crucial insights into how genetic information encoded in DNA and RNA is expressed through protein synthesis. This work was instrumental in proving the triplet nature of the code, meaning three nucleotides (a codon) correspond to one amino acid. Chemical Synthesis of DNA and RNA: Khorana was at the forefront of chemically synthesizing DNA and RNA molecules with defined sequences. He developed methods for synth...

Janaki Ammal: The Botanist Who Changed Indian Agriculture Edavalath Kakkat Janaki Ammal:  India's pioneering botanist and agricultural revolutionary Edavalath Kakkat Janaki Ammal (1897–1984), commonly known as Janaki Ammal, was a trailblazing Indian botanist and plant cytologist whose contributions significantly shaped Indian agriculture and plant science. Her life and work are marked by scientific brilliance, unwavering dedication, and a fierce commitment to biodiversity conservation. Early life and education Born in Thalassery, Kerala in 1897, into a cultured and educated middle-class family. Her father, a sub-judge with a keen interest in natural sciences, fostered her early love for botany. Defying the societal norm of early marriages for women at the time, Janaki chose to pursue higher education, an uncommon path for women in India and worldwide during the early 20th century. She completed her Bachelor's degree from Queen Mary's College, Madras and an Honours degree i...

Meghnad Saha: The Astrophysicist Who Measured the Stars Meghnad Saha: the astrophysicist who measured the stars Meghnad Saha (1893-1956) was an Indian astrophysicist renowned for his groundbreaking work in thermal ionization and its application to understanding stellar spectra. He is best known for developing the Saha ionization equation, a crucial tool that transformed stellar spectroscopy from a qualitative classification method into a precise technique for quantitative measurements. This equation is still relevant in stellar physics today. Saha ionization equation Saha's equation, developed in 1920, relates the ionization state of a gas in thermal equilibrium to its temperature and pressure. It is derived by combining principles of quantum mechanics and statistical mechanics. This allowed astronomers to accurately determine the actual temperatures of stars based on their spectral classes, a groundbreaking achievement at the time. Applications Beyond its use in stellar astrophy...